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Immunology Investor Event

sanofi Substantial growth potential for AD Adult advanced therapy penetration in years after launch (in %) Psoriasis Atopic Dermatitis I 2% 1% 8% 2022 I 5% 9% 16% AD market expected to continue to grow faster than Psoriasis given high unmet need and competitive entrants AD adult penetration progressing strongly in the U.S. at 8% in the 5th year of launch, significantly ahead of Psoriasis market development We estimate adult penetration to be over 25% while adolescent and pediatrics in the 10-16% range in 10yrs Year 1 Year 5 Year 10 Year 15 Psoriasis¹ 2 4 AD1 1 42 7 7+ 12 7+ 1. Number of advance therapies; Atopic Dermatitis: estimated, pending Ph2/3 readouts 2. Abrocitinib, upadacitinib, tralokinumab and dupilumab Source: Treated patient counts directly from DRG/Clarivate 2018 report 11 Immunology Investor Event
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