BioNTech Investor Day Presentation Deck
Digital & AI/ML
(2) COVID-19 variants monitoring and prediction
EWS report: June 24, 2022
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Mutations commonly found in lineage
not commonly found in lineage
Mutations
NTD Region (14-303)
RBD Region (319-541)
T191¹
L24-7
P25-16
P26-16
A27S¹
Y38H
A67V¹
H69-4
V70-5
T951¹
E96D
G142
G142D¹
V143-16
Y144-5
Y145-8
F157S
L176F
D178N
N211-18
L2121¹
V213F
V213G¹
R214S
ins214EPE
L242-
A243-5
L244-¹0
W258R
F329C
1332F
T333K
L335F
C336G
C336Y
P337S
G339D¹
E340D
E340K²¹
F342L
R346K¹
R346T2¹
S371F¹
S371L¹
S373P¹
$375F¹
T376A¹
P384L
V395L
D405N¹
B4085
K417N¹
K417T
N440K¹
G4465¹
L452M
L455F4
L455S
L455W
F456L14
K458M
S477N¹
T478K¹
E484A¹
E484V
Q493R¹
G4965¹
Q498R¹
N501Y¹
Y505H¹
Antibody Escape
H5190
A520T
K537R
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