Investor Presentaiton

Screening Early Disease Detection Minimal Residual Disease Recurrence Detection & Surveillance Therapy Selection Advanced Cancer Care >120M Average-Risk Individuals shield™ GUARDANT™ Cancer Detection >15M Early-Stage Patients and Survivors Surgery +/- Adjuvant GUARDANTREVEAL Recurrence >700K Advanced Cancer Patients INVESTOR 20 DAY 23 1st Line Tx 2nd Line Tx +Tx FDA Approved GUARDANT 360CDX GUARDANT 360 GUARDANT 360 TissueNext™ GUARDANT 360 Response 59 59

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