Retail Banking Performance Update

Mexico (Constant EUR mn) Change Change Q1'21 Q2'21 Q3'21 Q4'21 Q1'22 Q2'22 Q3'22 Q4'22 Q4'22/Q3'22 2021 2022 2022/2021 Net interest income 767 774 787 819 820 863 919 964 +4.9% 3,146 3,565 +13.3% Net fee income 236 240 226 237 267 287 292 294 +0.6% 939 1,140 +21.3% Gains (losses) on financial transactions and other (7) (19) 6 (34) (18) (22) (36) (6) -84.9% (54) (82) +52.5% Total revenue 996 995 1,020 1,022 1,068 1,128 1,174 1,252 +6.6% 4,032 4,623 +14.7% Operating expenses (432) (433) (475) (524) (470) (504) (519) (583) +12.3% (1,864) (2,076) +11.4% Net operating income 563 562 544 498 598 624 655 669 +2.1% 2,168 2,547 +17.5% Net loan-loss provisions (264) (233) (237) (163) (199) (185) (181) (223) +23.4% (897) (788) -12.2% Other gains (losses) and provisions (6) (7) (1) (7) (29) (26) (38) (1) -97.1% (22) (94) +328.6% Underlying profit before tax 293 322 305 328 370 412 437 445 +1.8% 1,249 1,665 +33.3% Underlying consolidated profit 222 247 253 273 280 312 329 336 +2.0% 996 1,257 +26.3% Underlying attributable profit 206 229 235 256 271 301 317 324 +2.0% 926 1,213 +31.0% Santander 42

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