Investor Presentaiton
Case Study: Novel Treatment
Age
60
Indications
Sex
Novel treatment for a Severe Progressive Silicosis related
Occupational Lung Disease
Baseline
Summary
•
.
At baseline, there are advanced changes of chronic, complicated silicosis as
marked by nodular coalescence and fibrosis in the apical regions bilaterally,
leading to progressive massive fibrosis.
No significant structural changes are seen after treatment (on CT).
Following treatment, there are functional improvements in all inspiratory
metrics visible on XV LVAS. Notably, the right apical region with areas of relative
underventilation (red shading) has markedly improved to average ventilation
(green shading) following treatment.
3 Months Post-WLL
Clinical Observations
Quantifiable, regional improvements in inspiratory function have
been observed following treatment for lung disease, which assists the
clinician in monitoring treatment effectiveness.
In comparison, serial chest CTs showed no significant change
following this treatment
TV
Structural CT
XV LVAS
0.5L
TV
Structural CT
XV LVAS
0.6L
4DMedical™
VH
54.5%
VDP
17.3%
VH
47.3%
VDP
13.5%View entire presentation