Investor Presentaiton slide image

Investor Presentaiton

IJMS INTERNATIONAL JOURNAL of MEDICAL STUDENTS XXVI CECIM S14 Abstracts Abstracts caused actually by G. sanguinis due to the lack of identification of the latter and the great similarity in morphology and biochemical test results. The available literature is scarce G. sanguinis. There has been a case of meningitis associated with G. Sanguinis after a surgical procedure on a patient 1 year old at the Central Military Hospital. Case report: Female patient, 1 year old, who came HOMIC with emesis, irritability, fever, altered state of consciousness and bulging anterior fontanelle. She have an antecedent of surgical pro- cedure (endoscopic ventriculostomy), with discharge six days ago due an adequate evolution. The paraclinics showed a G. sanguinis (tipification in LCR with StrepⓇ kit). Vancomicin and cefepime is ad- ministrated to the patient with satisfactory evolution, and discharge. Conclusion: The meningitis caused by unusual microorganism have a low frequency, clinicians should be vigilant about that germs, rapid diagnosis and treatment ensures proper patient recovery and less serious sequelae. Keywords: Gram positive cocci, Meningitis, Gram Positive Bacterial Infections. 04 Sarcoidosis: A Diagnostic Challenge. Jorge De Jesús Gómez Villa, Belis Teresa González Cogollo, Danith Judith Estrada Osorio, Omar Enrique Cárdenas Luque, César Redondo, Karina Ruíz Cáez, Liney Mendoza Suárez. Scientific Society: Asociación Científica Acta médica de Carta- gena, ACAMC. Introduction: Sarcoidosis is a chronic granulomatous disease of unk- nown cause, histologically characterized by the presence of nonca- seating granulomas. The course of the disease is variable, presenting possible remission periods during its evolution. The lungs are the sites more frequently implied and the most common reason of mor- bidity and mortality. Its highest incidence rates are in the northern European countries (5 to 40 cases per 100.000 inhabitants). Case re- port: 50-year-old feminine patient, to whom an incidental finding of hepatic nodules is made during cholecystectomy, which are biopsied with a histopathology result of chronic granulomatous inflammation. In subsequent consultations, patient reports clinical picture of diffi- culty breathing, cough and diffuse abdominal pain. A thoracoabdo- minal CT is ordered, with a final report that demonstrates multiple nodules with predominance of the right lung. Clinical impressions are made of malignant neoplasia of lung, pulmonary tuberculosis and fewer probable sarcoidosis. A new biopsy of the nodules is per- formed and it shows noncaseating chronic inflammation, consistent with infectious process. It was considered appropriate to start anti- tuberculosis antibiotic treatment with the standard scheme. After 6 months of treatment, the clinical picture persists, and new hysto- pathologic, histochemical and PCR exams are ordered, concluding the diagnosis of sarcoidosis. Conclusion: Sarcoidosis is a systemic disease, a challenge of diagnosis due to its variable morbidity, low incidence and geographical distribution. Other more frequent patho- logies, like infections or malignancies, must be ruled out and specific studies should be done to reach the diagnosis of this illness. Keywords: Diagnosis, granuloma, inflammation, multiple lung nodu- les. 05 Cerebrovascular Events In Young Patients: Coexisting With Acquired Thrombophilia. Santiago Loaiza Betancurt, Lisceth Paola Quintero González, Aída María Gonzáles Correa. Scientific Society: Asociación Científica de Estudiantes de Medicina de Universidad de Caldas, ACEMCAL. Introduction: The strokes acquire a major epidemiologic importance in patients over 65 years old and associated to heart and metabolic diseases. Nevertheless, this type of events in patients under 30 years old, is usually associated to other etiologies, like acquired prothrom- botic disorders such as Antiphospholipid Syndrome. Case report: In this particular case, the patient is a young woman with 18 years old, and she has experienced two clinical episodes compatible with a stroke, the first of them involved headache and right paresis; the second event occurred two months later, consisting of palpitations and right paresis as well. At her physical examination, the malar rash or "butterfly rash" is notable, referred as constant since two years ago by the patient. After the first described event, several studies were performed in order to establish its etiology, like a Holter that showed alterations compatible with Variable Atrial Fibrillation, which encourages the start of anticoagulation with Rivaroxaban, besides Amiodarone. Likewise, in order to find an underlying autoimmune disorder, different specific blood antibodies are measured, finding high titers of lupus anticoagulant and IgG anti-ẞ2-glycoprotein, and a more extended partial thromboplastine time. Conclusion: This par- ticular case becomes interesting given the pharmacological control of the cardiac arrhythmia when the second stroke occurred, making more likely the coexistence of a prothrombotic disorder that had triggered the event; likewise one of the main goals is establishing an anticoagulation scheme that shall be effective for both pathologies. Keywords: Anticoagulation, antiphospholipid syndrome, atrial fibri- llation. 06 Umbilical Myiasis In A Neonate From Colombia, Case Report Juan David Ruiz Zapata, Luis Mauricio Figueroa Gutiérrez, Jaime Alberto Mesa Franco. Scientific Society: Asociación Científica de Estudiantes de Medicina de Risaralda, ACEMRIS. Introduction: Myiasis is the infestation in live vertebrate animals, including humans, with dipterous larvae. It is distributed around the world in tropical areas with low socio-economic levels and pre- sence of cattle. Neonatal umbilical myiasis is an important cause of death in bovines and produces major economic losses in livestock. However, its presentation in humans is rare, with 9 cases reported worldwide. Case report: A 7 days old newborn was taken to the hospital because she had sero-hematic discharge, foul smelling and visualization of larvae in the umbilical stump. On admission, a blood test showed leukocytosis, and two blood cultures at admission and 48 hours later were negative. The umbilical stump was covered with gauze soaked in ivermectin and nitrofurazone. Due to the risk of late onset sepsis, intravenous oxacillin and gentamicin were admi- nistered. In total, 55 larvae were removed from the wound and the patient recovered without complications. The causative agent was identified as Cochliomyia hominivorax. Conclusion: Cochliomyia ho- minivorax is an obligated parasite in its larval state, which invades open wounds and can penetrate deeply, causing tissue destruction and peri-lesional inflammation that facilitates bacterial superinfec- tion. Umbilical myasis is especially dangerous because of the risk of migration to deeper tissues, omphalitis and sepsis. The management of this disease includes the administration of antiparasitics, applying toxic substances to facilitate the larvae extraction and antibiotic treatment for the prevention of secondary infections. Keywords: Cochliomyia, neonate, umbilicus. 07 Flu-Like Syndrome In A Patient With Antitubercular Therapy Andrés Gaviria Mendoza, Nini Johana Erazo Bravo, Andrés Gaviria Mendoza, Jorge Enrique Machado Alba. Scientific Society: Asociación Científica de Estudiantes de Medicina de Risaralda, ACEMRIS. Introduction: The flu-like syndrome is a clinical state characterized by fever, malaise, headache, myalgia and vomiting that can be ge- nerated by different infectious agents or drugs, including interfe- ron, bisphosphonates and levamisole. A case of flu-like syndrome induced by antitubercular therapy in a first level hospital (Pereira, Colombia) is presented. Case report: A 69 years-old man, living in crowded conditions in urban area of Pereira. He had presented cough with purulent sputum, fatigue and night sweats for 4 months. Se- rial sputum smear was reported as positive. Treatment began with Rifampicin + Isoniazid + pyrazinamide + ethambutol, three tablets daily. Three hours after consumption of antitubercular treatment the patient presents with malaise, chills, vomiting and fever. The next day he reported improvement of his condition, but upon taking the second therapy dose, the referred symptoms recurred. Considering that the flu-like syndrome has been described as an adverse reac- tion to antitubercular therapy (especially rifampin), the chronologi- cal relationship of symptoms with intake/re-administration of drugs and improvement of the case when consumption was avoided, the diagnosis of flu-like syndrome was done. Conclusion: The flu-like syndrome is a rare entity that must be promptly identified to seek al- ternative therapies and avoid hindering the diagnosis, management and the patient adherence to pharmacotherapy. Keywords: Adverse Drug Reaction, Flu-like syndrome, Pulmonary tu- berculosis, Rifampin, Therapeutics. 08 Massive Empyema By Streptococcus Constellatus, Case Re- port Felipe Vera Polanía, Julián Andrés Hoyos Pulgarín, Alexander Alzate. Scientific Society: Asociación Científica de Estudiantes de Medicina de Risaralda, ACEMRIS. Introduction: Streptococcus constellatus is a member of the group now called Streptococcus anginosus, which includes 3 species. These microorganisms are considered normal flora of the mouth, throat, gastrointestinal and genitourinary tracts, but can cause opportunistic infections such as pharyngitis, bacteremia and have been associated with serious purulent infections. In this paper the case of a patient with an unusual presentation of infection by S. constellatus with multiorgan involvement is described. Case report: Presents the case of an adult male patient with no relevant medical history who pre- sented to emergency department with nonspecific abdominal pain, whose laboratory test results show an important systemic inflamma- tory response and in whom is achieved to establish Streptococcus constellatus spp constellatus, with radiographical evidence of mul- tiorgan abdominal engagement, with poor response to medical and surgical management. Conclusion: As this is the first case report of infection by S. constellatus found in the national literature is deci- ded describe for the unusual presentation of massive empyema and severe septic shock, so that future studies be undertaken to enable facilitate early recognition of this disease, assess risk factors and prognostic factors. Keywords: Streptococcus constellatus, Gram-Positive Bacterial Infec- tions, Gram-Positive Bacteria, Empyema, Septic Shock. 09 Urofacial Ochoa's Syndrome (UFOS): A Case Report Of 16 Years of Clinical Evaluation In Medellín, Colombia. Pérez Velásquez Camilo Andrés, Osorio Rico Sebastián, Quin- tero Vanegas Santiago, Cristian David Ramírez Lujan, Laura Elisa Villegas Sierra, Paul Bryan Vélez Taborda. Scientific Society: Asociación de Estudiantes de Medicina de la Universidad de Antioquia, ASCEM-UDEA. Introduction: The Urofacial Ochoa's Syndrome (UFOS) is characteri- zed by inversion of facial expression and bladder dysfunction, spe- cifically non neurogenic neurogenic bladder without any obstructive abnormality. There have been reported about 100 cases of this syn- drome and according to researches the mutation of the gene that is associated with the symptoms has been mapped to chromosome 10923-924. This syndrome is recessively inherited. Case report: A case of an 18-year old young man with urofacial syndrome is repor- ted. He was diagnosticated at 2 years of age because of absence of bladder and bowel control, frequent urinary infections and inversion of his facial mimic. There was not any familiar antecedent the syn- drome present. Based on that, many clinical examinations and diag- nosis as well as chirurgical procedures have been done. They include a vesicostomy at age 4, where thick bladder walls were observed, a barium enema because of the constant constipation, where an alte- red function of the colon was diagnosticated. A Mitrofanoff procedu- re was done at age seven as well as a clam ileocistoplasty. At age 10, a renal echography showed mild bilateral hydroureteronephrosis, which was more severe in the left kidney. Since age 13, the patient has been stable and presents oliguria, but his paraclinical studies are within normal limits. Conclusion: His signs and symptoms are very similar to those observed in the description of the UFOS. He was clinically diagnosed, so it is important to do genetical and neurop- sychological studies to him and his family to confirm the diagnosis. Keywords: Urofacial Ochoa's Syndrome, neurogenic bladder, Elimina- tion dysfunction. INTERNATIONAL JOURNAL of MEDICAL STUDENTS www.ijms.info • 2015 Vol 3 Suppl 1 www.ijms.info . 2015 Vol 3 Suppl 1 XXVI CECIM INTERNATIONAL JOURNAL of MEDICAL STUDENTS S15
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