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Investor Presentaiton

Appendix (Research and Development) Main Events / Targets for FY2022 (as of May 15, 2023) Psychiatry & Neurology ✓ ulotaront (SEP-363856) ✓ ✓ Completed action/target Revisions since the announcement of January 2023 are shown in red Adjunctive major depressive disorder ✓ Generalized anxiety disorder Start clinical studies for two new indications Advance Phase 3 study in the U.S. and Phase 2/3 study in Japan and China for schizophrenia SEP-4199: Advance Phase 3 studies for Bipolar I depression Oncology ☑ relugolix (Europe) Obtain approval for prostate cancer Advance early Phase studies Regenerative ☐ Allogeneic iPS cell-derived products (AMD: age-related macular degeneration): Start clinical study in Japan Allogeneic iPS cell-derived products (Parkinson's disease): Start clinical study in the U.S. medicine/ Cell therapy Infectious Diseases Others Frontier ✓ Start construction of manufacturing plant in the U.S (for RETHYMICⓇ and allogeneic iPS cell-derived products) KSP-1007 (Antimicrobial resistance) : Complete Phase 1 study in the U.S. universal influenza vaccine, malaria vaccines: Promote joint research and development projects relugolix : (U.S.) (Europe) Obtain approval for endometriosis Submit MAA for endometriosis ✓ Launch products: ✓ (Japan) MELTz Neurorehabilitation device for hand/fingers (U.S.) VR contents for mental health (brand name: First Resort, general wellness product) Promoting the current themes and generating evidence data for maximizing the value of the launched products: Digital device for relieving BPSD, etc. Sumitomo Pharma © Sumitomo Pharma Co., Ltd. All Rights Reserved. 23
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