Q1 2022 Results slide image

Q1 2022 Results

Company overview Financial review 2022 priorities Appendix References 1 GROWTH KisqaliⓇ delivers double-digit growth across regions CEZ KISQALI K L Sales evolution USD m, % cc Ex-US US +28% cc 239 195 160 124 71 79 Q1 2021 Q1 2022 ■ CDK4/6 (TRX) market trending towards recovery to pre-COVID levels; US growth mainly driven by adjuvant use ■ KisqaliⓇ grew 28% cc vs. PY; US growing in line with market, Europe growing ahead of market ■ MONALEESA-2 results published in NEJM, showing ~5 years median overall survival, longest ever reported in aBC ■ NATALEE adjuvant study primary analysis now expected 2023 In ph3 randomized controlled trials, ribociclib + endocrine therapy has shown overall survival benefit in the first-line setting. 11 Investor Relations | Q1 2022 Results NOVARTIS | Reimagining Medicine
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