Q3 2022 Results slide image

Q3 2022 Results

Company overview Financial review 2022 priorities Appendix References Pluvicto™ continues strong start in the US 1 GROWTH PLUVICTO™ Rapid launch uptake in US Q3 sales of USD 80m; NBRx share 14% in post-taxane mCRPC Over 120 centers actively ordering; focus in Q3 on smooth supply and customer service More than 75% of insured lives covered (across Medicare, Medicaid and private payers) Permanent A code effective in October Preparing for further expansion ✓ Steadily expanding treatment centers in the US ✓ Significantly increasing manufacturing capacity (Ivrea in 2022; Millburn and Indianapolis planned in 2023) Positive CHMP opinion²; expected EU rollout 2023 ✓ Earlier line studies on track: ■ PSMAfore (pre-taxane) readout expected YE 20221 ■ PSMAddition (mHSPC) readout expected 2024 CHMP Committee for Human Medicinal Products NBRX - New to Brand prescriptions mCRPC metastatic castration-resistant prostate cancer 13 Investor Relations | Q3 2022 Results 1. Event-driven, could move to early 2023. 2. Oct 2022. ✓ NOVARTIS | Reimagining Medicine
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