Innovent Biopharmaceutical Transformation slide image

Innovent Biopharmaceutical Transformation

Commercial: Expanded Strategic Partnership with Lilly in Oncology in Commercialization of Multiple Late-Stage Products Expand Innovent and Lilly's strategic partnership in oncology including multiple late-stage products ✓ Further validates Innovent's commercial platform and capability Further expand Innovent's rich oncology pipeline by adding one approved product, one NDA product, and potentially a one late stage product, providing integrated patient solutions with strong portfolio synergies Enhance Innovent's franchise in major cancer indications including NSCLC, GC and HCC, as well as potentially hematological malignancies Innovent will receive... • Sole commercialization rights to import, market, promote, distribute and detail CyramzaⓇ (ramucirumab) and RetsevmoⓇ(selpercatinib) in mainland China Right of first negotiation granted to Innovent for potential future commercialization of pirtobrutinib in mainland China CYRAMZA™ ramucirumab injection 10 mg/ml solution China approval for GC in Mar 2022, NDA for HCC submitted in Sep 2021 Retevmo™ China NDA submitted in Aug 2021 Pirtobrutinib (Global Phase 3 ongoing) GC HCC NSCLC new case new case 480K 410K new case 650K Late-stage DTC/MTC Pirtobrutinib new case is an Orally Active, Highly Selective and non-Covalent BTK Inhibitor 4 58K Leverage two parties' strengths in a win-win manner to continue bringing innovative medicines to benefit Chinese patients Innovent Confidential Copyright©2022 Innovent Lilly Will receive... Upfront payment - $45m in total upon regulatory approvals of CyramzaⓇ in HCC and RetsevmoⓇ in NSCLC • Responsible for manufacturing and supply of CyramzaⓇ and RetsevmoⓇ 7
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