Q1 2023 Results slide image

Q1 2023 Results

Company overview Financial review Conclusions Appendix References KisqaliⓇ gaining momentum globally, with increasing recognition of its differentiated profile GROWTH Sales evolution USD m, % cc Ex-US US +81% 415 233 239 160 79 US metastatic BC NBRx share1 R3M, % 13% 182 Q1 2022 Q1 2023 Feb 2022 KISQALI 28% Q1 sales USD 415 million, +81% cc US NBRX1 share doubled vs. PY to 28% EU5 1L MBC NBRx share up to 38% (Q4'22) vs. 32% (in Q3'22) Feb 2023 Favorable NCCN2 guidelines positioning Kisqali as only Category 1 treatment for 1L mBC with Al Positive readout of Ph3 NATALEE study in eBC; data to be presented at upcoming congress mBC metastatic breast cancer. NBRX new to brand prescription. R3M rolling 3 months. Q1 R3M. 2. NCCN Guidelines updated as of 27-Jan-2023. eBC - early breast cancer. NCCN national comprehensive cancer network. Al-aromatase inhibitor. 1. Of CDK4/6 mBC market, US 16 Investor Relations | Q1 2023 Results ✓ NOVARTIS | Reimagining Medicine
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