Half-Year 2022 Financial and Clinical Trials Update slide image

Half-Year 2022 Financial and Clinical Trials Update

2022: Key late-stage news flow* and upcoming IR events Regulatory Phase III/ pivotal readouts Compound Vabysmo Susvimo Lunsumio (mosunetuzumab) Tecentriq Hemlibra Polivy + R-CHP glofitamab Tecentriq + tiragolumab + chemo Tecentriq + chemo Tecentriq + tiragolumab Tecentriq giredestrant Tecentriq + Avastin Venclexta + dexamethasone Tecentriq + chemo Tecentriq + tiragolumab + chemo Alecensa gantenerumab Susvimo Susvimo Indication nAMD/DME nAMD 3L+ FL Adjuvant NSCLC Mild to moderate hemophilia A 1L DLBCL 3L+ DLBCL 1L ES-SCLC Adjuvant SCCHN 1L PDL1+ NSCLC Adjuvant RCC 2/3L HR+ MBC Adjuvant HCC t(11;14) R/R MM Neoadjuvant NSCLC 1L esophageal cancer Adjuvant ALK+ NSCLC Alzheimer's disease DME DR Milestone US/EU approval US EU approval 2023 US/EU approval EU EU approval EU approval EU/US approval Ph lb NP30179 Ph III SKYSCRAPER-02 Ph III IMvoke010 Ph III SKYSCRAPER-01 Ph III IMmotion010 Ph II acelERA Ph III IMbrave050 Ph III CANOVA Ph III IMpower030 Ph III SKYSCRAPER-08 Ph III ALINA Ph III GRADUATE 1/2 Ph III PAGODA Ph III PAVILION EU x 2023 Continues to OS IA Х 2023 Virtual event Angiogenesis Monday, 14 February 16:30 to 17:45 CEST Virtual event MDA Wednesday, 16 March 16:30 to 17:30 CEST Roche ESG Day Access to Healthcare Monday, 16 May 15:00 to 16:30 CEST Virtual event ASCO Roche Pharma Day Virtual event London ASH Monday, 12 September TBA 10:00 to 15:00 BST Monday, 6 June 16:00 to 17:30 CEST * Outcome studies are event-driven: timelines may change; OS-overall survival; IA=interim analysis Roche الله 33
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