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Investor Presentation

128 Investor presentation First six months of 2022 NAO remains committed to its strategic aspiration of transforming 70% of US sales by 2022 The strategic aspiration is to transform 70% of sales Strategy Framework for North America Operations 100% 80% 60% 40% 20% 0% 2015 Obesity care New insulin launches H1 2022: 71% Aspiration: 70% 2022 New GLP-1 launches VictozaⓇ Mature insulin Rare disease NAO: North America Operations New insulin launches includes: TresibaⓇ, Xultophy®, FiaspⓇ and follow-on brand insulin; New GLP-1 launches includes: OzempicⓇ and RybelsusⓇ NAO Maximise the semaglutide molecule OZEMPIC RYBELSUS® semaglutide injection semaglutide tablets ONCE-WEEKLY wegovy semaglutide injection 2.4 mg Insulin (price pressure) Manage foundation Rare disease (sustained growth)
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