Investor Presentaiton

LOVVOLUS JEUVEAU EXTRA-STRENGTH PHASE II DURATION STUDY BASELINE CHARACTERISTICS PraB E-S 40U N=51 OnaB 20U N=50 PraB 20U N=53 AGE IN YEARS, MEAN (RANGE) 46.8 (20, 69) 47 (25,72) 46.8 (22,72) GENDER FEMALE N (%) MALE N (%) RACE 48 (94.1%) 47 (94.0%) 50 (94.3%) 3 (5.9%) 3 (6.0%) 3 (5.7%) ASIAN 0 (0%) 1(2%) 1 (1.9%) BLACK OR AFRICAN AMERICAN 3 (5.9%) 2 (4%) 3 (5.7%) WHITE 48 (94.1%) 47 (94.0%) 49 (92.5%) De 17

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