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Investor Presentaiton

2023 GUIDANCE Prior Updated REVENUE $31.2 $31.7 billion $33.4 $33.9 billion GROSS MARGIN % OF REVENUE (GAAP) GROSS MARGIN % OF REVENUE (NON-GAAP) Approx. 77% Approx. 79% Approx. 78% Approx. 80% MKTG, SELLING & ADMIN. $7.0 $7.2 billion $7.2 $7.4 billion RESEARCH & DEVELOPMENT ACQUIRED IPR&D OTHER INCOME/(EXPENSE) (GAAP) OTHER INCOME/(EXPENSE) (NON-GAAP) TAX RATE EARNINGS PER SHARE (GAAP) EARNINGS PER SHARE (NON-GAAP) Assumes shares outstanding of 903 million Not for promotional use $8.3 $8.5 billion $8.9 $9.1 billion $105 million $202 million - $(200) $(100) million $(75) - $25 million $0 $100 million Approx. 13% 14% - 15% $8.18 $8.38 $8.65 - $8.85 $9.20 - $9.40 $9.70 - $9.90 2023 Q2 EARNINGS Lilly COMMENTS Increased range reflects revenue from the sales of rights for Baqsimi and olanzapine as well as strong performance in underlying business Increase driven by the sales of rights for Baqsimi and our olanzapine portfolio Increase reflects additional investments in recent launches and preparation for launches expected later this year Increase reflects additional investments in the late-stage portfolio and early-stage research and expected incremental expense from business development activities Incorporated IPR&D charges that have been incurred through Q2 2023; does not include any IPR&D charges associated with potential or pending business development transactions Increase driven by the interest impact of higher cash balances; reported guidance incorporates net losses on investments in equity securities Increase reflects the impact from the sales of rights for the olanzapine portfolio and Baqsimi FX assumptions: 1.12 (Euro), 139 (Yen) and 7.1 (Renminbi) 13
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