Investor Presentaiton slide image

Investor Presentaiton

GOD Potency sanofi All four LNP components leave significant room for optimization 84 Vaccines Investor Event Ionizable lipid Helper lipid Cholesterol The ionizable lipid wraps around the mRNA and helps transport and release it to the targeted cell The helper lipid helps create the lipid membrane of the LNP, and it allows for the LNP to easily fuse to the mRNA's target cell and endosomal membrane Cholesterol enhances the stability of the LNP and ensures it is sturdy and rigid. This assists with the introduction of the mRNA into the cells PEGylated lipid Polyethylene glycol, or a PEG lipid, is what helps maintain the overall physical nanostructure of the LNP and protects the mRNA nanoparticles from the body's natural clearance mechanisms
View entire presentation