Investor Presentaiton

• TCB008 in vitro Safety Testing TC BIOPHARM The safety of TCB008 was confirmed in an off-target cytotoxicity assay against primary human monocyte derived macrophages - healthy counterpart for AML • TCB008 at doses of effector: target that exhibited potent cytotoxicity against two cancer cell lines did not exhibit off target cytotoxicity against the healthy control cells. 100 Cytolysis (%) THP-1-AML Cell Line T98G Glioblastoma Cell Line 80 60 60 40 40 20 20 THP-1 T98G Donor 1 Monocyte derived macrophages Donor 2 Donor 3 H ㅓ 0 HO 1:1 4:1 8:1 1:1 4:1 8:1 1:1 4:1 8:1 1:1 4:1 8:1 1:1 4:1 8:1 E:T 8 TCB008 Lot 1 - TCB008 Lot 2 TCB008 Lot 3

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