Investor Presentaiton

Genio Expected to Capture approx. 50% Market Share Independent 25 Clinician Survey Guidepoint Survey Sample size 25 clinicians 12 US ENTS + 4 German ENTS • • • 9 US Sleep Specialists Driving features in Genio adoption Physician Profile Clinicians at least "somewhat familiar" with Genio and Inspire systems ENTS/Sleep Specialists - Average annual HGNS implants/referrals = 40/47 5.0 4.5 4.2 Scalability-Latest-and-greatest technology with no extra surgery 3.9 4.0 - No implantable battery – No need to replace depleted battery 3.5 • 1.5T & 3T full-body MRI compatibility - Peace of mind No CCC diagnosis required with CCC label expansion - No DISE Single-incision - Less trauma and faster procedure Genio Mix upon US availability 10 10 2.9 3.0 2.5 2.0 1.5 1.0 0.5 3.6 3.6 4.4 3.8 3.7 3.6 0.0 Leadless Full MRI Compatiblity Implant for Life Miminal Scar/Implant not Visible Single vs Double Incision Fully Scalable Bi-Lateral System Faster Stimulation Indication/No Procedure CCC DISE US ENTS n=12 49% 51% Genio Other US Sleep Experts - n=9 46% 54% Nyxoah Genio Other

View entire presentation