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Novartis Q4 Results

Content Click below to navigate through the document Novartis delivers strong full year performance with margin expansion. Continuing innovation momentum with multiple positive Ph3 readouts ↓ ↑ Company overview Core margin 36.0% (+240 bps) Core Oplnc USD 16.4bn Several major innovation milestones in Q4 FabhaltaⓇ (iptacopan) US approval in PNH CosentyxⓇ US approval in HS Cosentyx® US approval of IV formulation (PSA, AS, nr-axSpA) Iptacopan Ph3 APPLAUSE study met its primary endpoint in IgAN Atrasentan Ph3 ALIGN study met its primary endpoint in IgAN Iptacopan Ph3 APPEAR-C3G met its primary endpoint in C3G ScemblixⓇ Ph3 ASC4FIRST met primary endpoints in 1L Ph+ CML-CP (Jan) Financial review Conclusions Appendix References Double-digit growth for sales and Core Oplnc for the quarter and full year¹ Growth vs. PY, CC Core margin 33.5% (+100 bps) 18% 13% 10% 10% Sales USD 11.4bn Core Oplnc USD 3.8bn Sales USD 45.4bn Q4 FY Successful spin-off of Sandoz FY 2024 guidance¹: Sales expected to grow mid single digit; Core Oplnc expected to grow high single digit Mid-term guidance¹ updated: Sales expected to grow +5% cc CAGR 2023-28; core operating income margin -40%+ by 2027 - Oplnc operating income. 1. As defined on page 37 of the Condensed Financial Report, Continuing operations include the retained business activities of Novartis, comprising the Innovative Medicines Division and the continuing Corporate activities Constant currencies (cc), core results are non-IFRS measures; explanation can be found on page 49 of Condensed Financial Report. Unless otherwise noted, all growth rates refer to same period in PY. □ NOVARTIS | Reimagining Medicine. Novartis Q4 Results | January 31, 2024 4
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