Investor Presentation H1 2023

133 Investor presentation First six months of 2023 Insulin market size and volume market share in Rest of World Insulin market share and market size (DKK billion) Total 59% 43% Long- acting 63% Fast- 2 acting Premix 83% 2 Human 68% 2 5 Novo Nordisk Competitors Rest of World Market growth A Market share Insulin volume: Market share 80% 20% 12 2.6% +0.9% 60% 15% 58% 10% 4.5% +1.5% 40% 5% 1.2% +0.4% 20% 2.9% +0.0% 0% May 2020 -0.1% +1.9% Source: IQVIA, May 2023; LHS graph - Value, RHS Graph - Volume, MAT; Share of growth not depicted due to too high numbers; NN: Novo Nordisk 0% -4% -5% -3% -10% May 2023 -NN market share -Market growth (right axis) NN growth (right axis)

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