EVOLUTION AT MERCK - INVENTING FOR LIFE

GEFAPIXANT (MK-7264): OPPORTUNITY FOR BROAD APPLICABILITY 10% global prevalence for chronic cough, of which ~20% are refractory chronic cough or unexplained chronic cough Endometrial- related pain Chronic cough Impacts ~176 million women worldwide ~29 million Americans suffer from sleep apnea, of which 80% are undiagnosed Other sensory functions Sleep apnea Potential pipeline in a product MERCK 3:: Mike Nally INVENTING FOR LIFE 72

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