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Investor Presentaiton

Strong business momentum Diversified portfolio growth 3 Efficient compounding engine Sustainable long-term growth Development-stage pipeline includes many potential launches... Adjusted Cash Receipts (1) ("top-line") Development-stage therapy candidates Therapy Omecamtiv Marketer(s) Cytokinetics Indication(s) Potential launch(2) Heart failure 2022 Incl. gantenerumab Zavegepant Biohaven/Pfizer Migraine 2023 PT027 AstraZeneca Asthma 2023 Otilimab GlaxoSmithKline Rheumatoid arthritis 2023 Seltorexant J&J MDD w/ insomnia symptoms 2023 Aficamten Cytokinetics OHCM 2024 BCX9930 BioCryst PNH 2025 $50 - 100m Pelabresib MorphoSys Myelofibrosis 2025 CPI-0209 MorphoSys Blood cancer and solid tumors 2025+ excl. gantenerumab Gantenerumab (incl. brain shuttle) Roche Alzheimer's disease 2023 / 2024 10 potential launches through '25 (gantenerumab excluded from guidance) $0 2020 2025e ROYALTY PHARMA MDD: Major depressive disorder; oHCM: Obstructive hypertrophic cardiomyopathy; PNH: Paroxysmal nocturnal hemoglobinuria. 1. See slide 114 for definitions and factors that may impact the achievement of our growth outlook. 2. All products are in Phase 3 development except: PT027 (ready to file), zavegepant (ready to file) and omecamtiv (filed); based on company disclosures and consensus sales estimates from Visible Alpha as of May 9, 2022. 42 92
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