Investor Presentation Full Year 2021 slide image

Investor Presentation Full Year 2021

135 Investor presentation Full year 2021 Novo NordiskⓇ US insulin net prices have declined in recent years, but vulnerable patients rely on our affordability offerings The US population by health insurance coverage Private insurance schemes | Government insurance schemes 7% Uninsured Net price development for Novo Nordisk products US Product portfolio¹ %, Change vs. Prior year 2017 2018 2019 2020 2021 • • Novo Nordisk insulin affordability offerings in the US My$99Insulin 30-day supply of a combination of Novo Nordisk insulin products (up to 3 vials or 2 packs of pens) for USD 99 NNPI unbranded biologics fast-acting (NovologⓇ) and premix insulin (Novolog® Mix) with 50% list price discount vs branded versions 46% List Price change - Avg² Net Price change - Avg² 6.9% 5.0% 5.5% 2.3% 2.0% -9.0% -8.6% -13.2% -16.9% -12.3% Human insulin for about USD25/vial at national pharmacies, including Walmart and CVS 47% Total US Insulin portfolio %, Change vs. Prior year 2017 2018 2019 2020 2021 • Patient Assistance Program free diabetes medication to people in need, annual income <400% above government defined poverty. Program 333 million people List Price change - Avg² Net Price change - Avg² -13.5% expanded during COVID-19 outbreak 6.3% 4.5% 4.4% 0.2% -14.8% -17.4% -27.7% -10.2% 0.0% • Immediate supply a short-term, immediate-need program offering free insulin for those at risk of rationing • Co-pay Savings Cards providing USD -100 million in assistance in 2021 for insulin to patients Note: Government insurance schemes cover Medicare, Medicaid and public exchanges, some of these with high deductibles Source: Centres for Medicare and Medicaid services, office of the actuary, National Health expenditures Projections; 1 NN US Product portfolio is inclusive of Diabetes, Obesity and Biopharm products; 2% change represents a sale weighted average list and net price for the respective calendar year compared to the sales weighted average list and net price for the prior year and is not reflective of the magnitude of individual list price actions • In 2021, more than 1 million people reached
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