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Investor Presentaiton

2030 Addressing high unmet medical need in Immunology, Cardiovascular & Neuroscience Immunology Cardiovascular 2023 Psoriasis $26B+ UC $7B+ PSA $5B+ $60B+ Pulmonary Fibrosis $5B+ Lupus $2B+ Alopecia $0.6B+ EOE $40M+ SjS $19M+ Psoriasis $33B+ Stroke $1.8B+ ACS $0.5B+ HFPEF $8B+ $30B+ CD $16B+ AF $19B+ ACS $0.2B+ Stroke $3B+ UC $10B+ HFPEF $5B+ Pulmonary Fibrosis $2B+ HCM $5B+ $75B+ $21B+ CD $18B+ Alopecia $1B+ PSA $6B+ Lupus $5B+ SjS $0.4B+ EOE $0.4B+ ll Bristol Myers Squibbâ„¢ *CV markets impacted by generic entry in Atrial Fibrillation Source: EvaluatePharma estimates; totals may not add due to rounding AF $8B+ MS $23B+ Neuroscience MS $21B+ ALS $1B+ Alzheimer's $1B+ $23B+ $38B+ Alzheimer's $12B+ ALS $3B+ Not for Product Promotional Use 149
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