Investor Presentaiton
IFNy spots/ 106 splenocytes
10000
1000
100
10
sanofi
Innovative multi-antigen vaccine candidate achieves targeted
immune profile, moving to phase 1/2 in 2024
Broad cross-serovar T cell
responses
Serovar D
Serovar E
Serovar F
Serovar G
Antigen A
LNP only
Spleen cells secreting Interferon-gamma
in mice immunized with mRNA encoding
Antigen A, or empty LNP control
Serovar equates to serotype terminology in chlamydia field
103 Vaccines Investor Event
ELISA titer anti-EB (log10EU)
w
Antigen B
Cross-serovar antibodies recognizing
native elementary bodies
LNP only
Serovar D
Serovar E
Serovar G
ELISA titer anti-EB (log10EU)
Antigen C
Serovar D
Serovar E
Serovar G
T
Antigen D
LNP only
Elementary body (EB) binding antibodies in sera from mice immunized
with mRNA encoding Antigen B, C, D or empty LNP controlView entire presentation