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Investor Presentaiton

Strong business momentum Diversified portfolio growth Efficient compounding engine Sustainable long-term growth ...expected to power growth through 2030 and beyond 2030e sales ($ in billions)(2) Illustrative 2030e Adjusted Cash Receipts (1) ("top-line") Therapy Risk adj. Potential '30 Non-risk adj. blockbuster Royalty rate (%) Omecamtiv $0.5 $1.8 Mid-single digits Incl. gantenerumab Zavegepant $1.1 $1.5 Low-single digits PT027 $1.0 $1.8 Low-single digits Otilimab $0.5 $1.2 Double digits (3) Seltorexant $0.4 $0.5 Mid-single digits Aficamten $1.9 $4.2 Mid-single digits Incl. gantenerumab BCX9930 $0.3 $0.6 Mid-single digits Pelabresib $0.4 $0.6 3% $400-800m CPI-0209 $0.0 $0.2 3% Total ~$6.0 ~$12.0 ~Mid-single digits $200-400m Gantenerumab $3.6 $8.1 3.3-4.2% (3) excl. gantenerumab (incl. brain shuttle) Risk adjusted (2030e) excl. gantenerumab Non-risk adjusted (2030e) ROYALTY PHARMA 1. See slide 114 for definitions and factors that may impact the achievement of our growth outlook. 2. Consensus sales estimates from Visible Alpha as of May 9, 2022; manual broker consensus sales for therapies without available Visible Alpha estimates. 3. Royalty Pharma is entitled to 80% of tiered double-digit royalties for otilimab and 60% of tiered 5.5% to 7.0% royalties for gantenerumab. 93
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