Investor Presentaiton

Research framework applied to Oncology builds on our scientific depth in tumor intrinsic mechanisms Strategy: Tumor Intrinsic Build a portfolio of foundational assets to address key tumor intrinsic and tumor extrinsic mechanisms, where combinations will be critical for durable responses with transformational potential. Ill Bristol Myers Squibb™ Oncogenic Drivers Lineage Specific || || We have emerging expertise in tumor intrinsic biology Clinical and pre-clinical programs targeted to specific tumor types and patient subsets DNA Damage Synthetic Lethal Insights from translational datasets demonstrate the relationship between tumor intrinsic and tumor extrinsic to guide rational combinations Not for Product Promotional Use 23

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