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Investor Presentaiton

6.12 Trends over time in cancer incidence Profile of Cancer and Related Health Indicators in the North East Region of India Crude Rate (CR) Per 100,000 Cancer Site 2004 2016 Oesophagus_F Ovary Rectum_M Breast F Oesophagus_M Liver_M 9.5* Oesophagus _F 2.2 4.9 8.5* Ovary 2.2 5.5 6.4* Rectum_M 2.5 4.2 5.7* Breast_F 12.3 19.4 4.6* Oesophagus M 15.3 21.0 4.5* Liver_M 4.7 5.4 Liver_F 3.6 Liver_F 2.6 3.3 Cervix Uteri 2.8* Cervix Uteri 17.9 20.1 Rectum_F 2.8* Rectum_F 2.6 3.3 All Site_F Lung_M Hypopharynx M Lung_F 2.5* All Site_F 102.4 138.4 2.4* Lung_M 18.0 18.7 1.8 Hypopharynx M 7.4 8.5 1.6 Lung_F 13.4 16.5 All Site_M 1.6* All Site_M 134.7 144.1 Nasopharynx_M 1.2 Nasopharynx M 2.5 3.6 Stomach_F -1.5 Stomach_F 11.2 11.9 Stomach_M -2.2* Stomach_M 35.2 25.2 -3 0 3 6 9 12 Annual Percent Change (%) Increase in APC, Decrease in APC, Increase or Decrease in APC for All Sites; * Significant Increase or Decrease at 95% Confidence Level Annual Percent Change (APC) in cancer incidence for all sites is observed to be 1.6% in males and 2.5% in females from 2004 to 2016. In females, an increasing trend has been observed for cancer of oesophagus, ovary, breast, liver, cervix uteri, rectum and lung, whereas stomach cancer has shown a decline. Among males, cancer of rectum, oesophagus, liver, lung, hypopharynx and nasopharynx show an increasing trend, whereas stomach cancer is declining. 99 ICMR National Centre for Disease Informatics and Research 10 Since 2011 icm NCDIR 20
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