Full Year 2023 Investor Presentation

139 Investor presentation Full year 2023 Insulin market size and volume market share in North America Operations Insulin market share and market size (DKK billion) Total Long- acting 37% Fast- acting 51% 59% Premix 6 24% Human 15 42% 76 16 101 NAO Market growth1 A Market share Insulin volume: Market share 60% 12% 199 -7.3% -0.9% -8.3% -1.2% 40% 8% 37% 4% 0% -4% -5.2% -0.8% 20% -4% -8% -7% -18.0% +0.8% 0% -12% Nov Νον 2020 2023 -5.8% -0.1% NN market share -Market growth (right axis) Novo Nordisk 1Market growth is YTD current vs YTD previous year Competitors NN: Novo Nordisk; Note: Insulin market numbers do not reflect rebates. Share of growth not depicted due to too high numbers. Market values are based on the list prices Source: IQVIA, Nov 2023, LHS graph - Value, RHS Graph - Volume, MAT, all countries -NN growth (right axis)

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