Q1 2023 Results slide image

Q1 2023 Results

Company overview Innovation: Pipeline overview Financial review Financial performance 2023 expected key events Regulatory Cosentyx® HS decisions Cosentyx® 2ml Al Cosentyx® IV Leqvio® Hypercholesterolemia Submissions Iptacopan PNH (US/EU/JP) KisqaliⓇ HR+/HER2- BC (adj) PluvictoⓇ mCRPC, pre-taxane (US) Readouts KisqaliⓇ HR+/HER2- BC (adj) Iptacopan IgAN Ph3 Iptacopan C3G Ph3 Ph3 starts Iptacopan in IC-MPGN LeqvioⓇ CVRR primary prevention lanalumab in immune thrombocytopenia lanalumab in systemic lupus erythematosus Conclusions Appendix Innovation: Clinical trials References Abbreviations H1 2023 EU H2 2023 US Status update - as of end Q1 US US JP, China US/EU JP US Filing expected in H2 US NATALEE Ph3 FIR Primary endpoint met at interim analysis APPLAUSE-IgAN Ph3 APPEAR-C3G Ph3 Ph3 Ph3 Ph3 Ph3 VICTORION-1P initiated 1L (VAYHIT1) and 2L (VAYHIT2) initiated SIRIUS-SLE 1 and 2 initiated HS hidradenitis suppurativa. C3G PNH - paroxysmal nocturnal hemoglobinuria. complement 3 Glomerulopathy. mCRPC metastatic castration-resistant prostate cancer. FIR - first interpretable results. IgAN - immunoglobulin A nephropathy. IC-MPGN - immune complex membranoproliferative glomerulonephritis. 32 Investor Relations | Q1 2023 Results INNOVATION U NOVARTIS | Reimagining Medicine
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