Corporate Presentation

Rare diseases SBS Short Bowel Syndrome (SBS) is a rare, chronic and debilitating condition High unmet medical need • SBS is a rare, chronic and debilitating condition resulting in impaired intestinal absorptive capacity 1.2 SBS is associated with significant medical complications including liver and renal failure, metabolic complications, chronic fatigue, and life-threatening infections³ Life-long dependency on parenteral support (PS) • SBS patients experience chronic dependence on complex PS to provide necessary nutrition and fluid intake and balance3 PS management is associated with a significant burden on health care systems and reduction in the patients' and caregivers' quality of life4,5 Need for improved treatment options • More effective and convenient treatments to further reduce PS is needed, with the ultimate goal of enteral autonomy³ ZBAL& ZEALAND PHARMA 1Jeppesen P., Expert Opinion on Orphan Drugs; 1:515-25, 2013; 2 Pironi, L, et al. Definitions of intestinal failure and the short bowel syndrome. Best Practice & Research Clinical Gastroenterology. 30(2), 173-185 (2016); 3 Cueda C et al. ESPEN Practical Guideline: clinical nutrition in chronic intestinal failure. Clin Nutrition 40; 5196-5120 (2021); 4 Belza et al. Stress, Anxiety, Depression and Health-Related Quality of Life in Caregivers of Children with Intestinal Failure on Parenteral Nutrition: A Cross-sectional Survey Study. JPEN J Parenter Enteral Nutr. 2022 Nov 6. doi: 10.1002/jpen.2461; 5 Winkler et al. Clinical, social, and economic impacts of home parenteral nutrition dependence in short bowel syndrome 38

View entire presentation