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Investor Presentaiton

ILUVIEN IMPROVES VISUAL ACUITY 70 Pre-ILUVIEN: Mean Change in Visual Acuity Mean Visual Acuity (VA; Letters) 68 55 4 5 5 2 3 2 2 2 50 54 52 56 64 66 62 60 58 wwwwwwww... -6.4 alimera Post-ILUVIEN: Mean Change in Visual Acuity 3222222 Mean Visual Acuity (VA; Letters) 64 63 62 61 67 66 65 70 69 68 * Denotes significance compared to baseline; p-value <0.05 * * * 65.45 64.89 64.91 * 63.64 63.94 * 65.97 +4.5 60 36 31 26 21 16 11 6 1 Baseline 3 6 9 12 Months Post-ILUVIEN 24 36 Months Pre-ILUVIEN n-value: 39 58 59 67 71 100 89 68 191 174 173 163 150 113 93 Source: Merrill et al. Am J Ophthalmol. 2023;248:16-23. Nasdaq: ALIM Data from Alimera's PALADIN Study All Eyes (n=202) 12
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