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Investor Presentation

24. Investor presentation First six months of 2022 Sales growth of 16%, driven by the GLP-1 portfolio for diabetes and obesity treatment Novo NordiskⓇ Novo Nordisk reported quarterly sales DKK billion 50 by therapy Reported sales CAGR¹: 8.0% 40 40 Reported sales for the first six months of 2022 Rare Other Rare endocrine rare blood disorders disease Reported sales and growth breakdown for the first six months of 2022 Therapy Sales (mDKK) Share of Growth growth Total GLP-12 36,651 45% 96% Long-acting insulin³ 8,900 -6% -5% disorders Premix insulin4 1% 5,513 -8% -4% -4.7%¹ 5% Fast-acting insulin5 8.729 -6% -5% Obesity 7% 30 Human insulin 4,163 -15% -6% 2.8%1 care 8% Total insulin 27,305 -8% -21% 2.9%1 Other Diabetes care 1,714 -16% -3% 20 8.8%¹ Total Diabetes care Obesity care7 65,670 15% 72% 7,045 84% 27% 10 79% Diabetes care Diabetes and Obesity care Rare blood disorders 72,715 19% 100% 5,940 3% 2% 0 Q2 2012 Other rare disease Rare endocrine disorders Rare blood disorders Q2 2022 Rare endocrine disorders Other Rare disease 10 Rare disease 3,743 -5% -2% 898 7% 1% 10,581 0% 0% Diabetes and Obesity care Sales of DKK 83.3 billion (+25%) Total 83,296 16% 100% Source: Quarterly company announcement 1 CAGR for 10-year period; 2 Comprises Victoza®, Ozempic®, Rybelsus®; 3 Comprises TresibaⓇ, XultophyⓇ and Levemir®; 4 Comprises RyzodegⓇ and Novo MixⓇ; 5 Comprises FiaspⓇ and NovoRapidⓇ; 6 Primarily NovonormⓇ, needles and GlucaGen® HypoKitⓇ; 7 Comprises SaxendaⓇ and Wegovy®: 8 Comprises NovoSeven®, Novo Eight®, NovoThirteen®, Refixia®, and EsperoctⓇ: 9 Comprises Norditropin and Macrilen TM; 10 Primarily Vagifem® and ActivelleⓇ Note: Sales numbers are reported in Danish kroner; Growth is at constant exchange rate, except for total sales growth of 24%; Refixia® and NovoThirteenⓇ are launched as RebinynⓇ and TRETTENⓇ, respectively, in North America.
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