Investor Presentaiton
Hematology
Reblozyl BET Inhibitor Breyanzi golcadomide Abecma
alnuctamab
GPRC5D
Confidence in Abecma's competitive profile further
reinforced by real world evidence
R/R MM Efficacy Outcomes¹
Best ORR
84%
73%
R/R MM Safety Outcomes¹
Best Response ≥ CR
Any CRS/Grade ≥3
Any NT/Grade ≥3
42%
33%
84%
82%
iber/mezi
ide-cel
RWE
Predictable safety profile
well understood
Real world data confirms
the efficacy profile in a
real world population
Strong manufacturing
reliability confirmed:
94% success rate
Data supports CAR T before
other BCMA-targeted
therapies in the real world²
18%
18%
5%
3%
3%
6%
ide-cel
KarMMa
ide-cel
RWE
ide-cel
KarMMa
ide-cel
RWE
ide-cel
KarMMa
ide-cel
RWE
ide-cel
KarMMa
ide-cel KarMMa (Phase 2 cohort), n=128
ide-cel RWE, n=159
Ill Bristol Myers Squibb™
1. Hansen DK, et al. J Clin Oncol. 2023;41:2087-97. 2. Ferreri CJ, et al. Blood Cancer J. 2023;13:117. Including antibody drug conjugate, bispecific antibody,
or BCMA CART on clinical trial
Not for Product Promotional Use
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