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FxG in Respiratory Disease & Beyond Cell type Macrophage Mast cells Fibroblasts T cell Sensory Neurons Endothelial cells Airway Smooth Muscle Dendritic cell Keratinocytes Disease opportunities* Broad immune: skin, lung, GI Urticaria, allergy, RA, eczema Fibrosis, lung, skin, RA, IPF Broad immune: skin, lung, Gl Respiratory, IBD, eczema RA, sarcoidosis, IBD, PAH Asthma, COPD, PAH Broad autoimmune: T1D, Graves Skin Copyright © 2024 23andMe, Inc. 23and Me 38

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