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Investor Presentaiton

Biome Australia 3 2.5 2 1.5 1 0.5 0 Baseline 3 days 14 days 3 2.5 2 * 1.5 1 0.5 0 Baseline 3 days 14 days Company Presentation | August 2023 * Commercial in confidence MEAN PLAQUE SCORE Key Product Research Placebo Chlorhexidine Biome Dental™ Probiotic *p<0.05 vs placebo **p<0.05 vs chlorhexidine MEAN GINGIVAL INDEX Placebo Chlorhexidine Biome Dental™ Probiotic *p<0.05 vs placebo **p<0.05 vs chlorhexidine The probiotic formulation in Biome Dental was compared to placebo and chlorhexidine mouthwash (standard treatment) in 60 healthy children. A significant decrease of plaque score and gingival index was seen on day 3 compared to placebo, and after 14 days of intake, these results persisted (p<0.05). At day 14, plaque score and gingival index were significantly better for Biome Dental compared to chlorhexidine (p<0.05). Sharma, P., Datta, G., Gandhi, K., & Kumar, D. (2019). A comparative evaluation of efficacy of probiotic and chlorhexidine mouthrinses on gingival health and plaque accumulation in 6-9 year old children. International Journal of Applied Dental Sciences, 5(1), 156-162. 25
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