GreenLight SPAC Presentation Deck
CBH
% BW Change from Baseline (Day 0)
MEAN + SEM
-10-
-15
GreenLight's Covid-19 vaccine candidate
Immune response protects against viral challenge
Hamster body weight change on virus challenge
0 1 2
3 4 5 6 7 8 9
Days Post Challenge
-
LNP Control
- Saline Control
• 100 μg
- · 30 μg
-.· 5 μg
10 11 12 13 14
GLB-COV-2-043
All doses of GreenLight vaccine protected hamsters
against weight loss following intranasal viral challenge
IC50 (1/serum dilution)
Investor Presentation | © 2021 GreenLight Biosciences. All rights reserved. GreenLight confidential.
Neutralizing antibody levels in hamsters
100000
10000-
1000-
100-
10-
1
ns
***
Mi
H
100 μg 30 μg
5 μg
GLB-COV-2-043
Day 21 (Pre-Boost)
Day 39 (Post-Boost)
GLuc Saline
Controls
Our GreenLight mRNA vaccine candidate induced high levels
of binding and neutralizing antibodies at all doses tested
HUMAN HEALTH
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