Investor Presentaiton

Net Interest Drivers Total Investments and Yield Spot Rate 4.56% Spot Rate Loans and HFI Yield 6.26% 4.45% 5.70% 3.66% 4.84% 2.77% 2.94% 2.51% 4.03% 4.19% 3.98% • $8.8 $2.2 $8.3 $8.6 $8.8 $2.8 $1.2 $7.5 $5.6 $4.8 $51.9 $52.2 $48.6 $39.1 $41.1 Q4-21 Q1-22 Q2-22 Q3-22 Q4-22 Total Investments Q4-21 Q1-22 Loans Q2-22 Q3-22 Loans, HFS Q4-22 Interest Bearing Deposits and Cost Spot Rate 2.21% Spot Rate Deposits, Borrowings & Cost of Liability Funding 1.88% 1.57% 1.97% 0.88% 1.03% 0.37% 0.25% 0.27% 0.38% 0.20% 0.21% $1.7 $6.1 $7.2 $7.2 $2.4 $33.9 $23.5 $23.7 $24.9 $19.7 $21.3 $30.0 $30.7 $28.6 $26.3 $33.9 $26.3 $28.6 $30.0 $30.7 Q4-21 Q1-22 Q2-22 Q3-22 Q4-22 Q4-21 Interest Bearing Deposits Dollars in billions, unless otherwise indicated WA Western Alliance Bancorporation® Q1-22 Q2-22 Q3-22 Q4-22 Interest Bearing Deposits Non-Interest Bearing Deposits ■Total Borrowings Highlights • Loan yields increased 86 bps in Q4 due to a higher rate environment Yield on Loans Held for Sale of 5.63% increased from 4.87% in Q3 Investment yields increased 79 bps in Q4, primarily related to floating-rate securities • Cost of interest-bearing deposits increased 94 bps, and total cost of funds increased 69 bps in Q4 to 1.57% due to higher costs on deposits and borrowings | 18

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