Investor Presentation Full Year 2017 slide image

Investor Presentation Full Year 2017

Investor Presentation Full year 2017 Slide 67 Significant growth in GLP-1 market with leading market share for VictozaⓇ Global GLP-1 market value and share of total diabetes care market value exenatide leading in all regions VictozaⓇ sales and GLP-1 value market share VictozaⓇ GLP-1 value market share VictozaⓇ DKK billion albiglutide1 70 60 50 exenatide 40 launch 30 20 10- 0 2005 dulaglutide lixisenatide GLP-1 share of total diabetes care market DKK billion FDA/EMA statement on pancreatic safety³ 14% 20 48% 18 12% 16 Dulaglutide Article on launch 10% 14 pancreatic safety 12 of incretins² - 8% 10 VICTOZA Tiraglutide injection: - 6% 8 - 4% 6 58% 4 2% 2 49% 41% 75% 68% 0% 0 2009 2013 2014 2017 North Region Region Region Region Region America Europe AAMEO J&K LATAM China 1 Manufacturing and sale of albiglutide to be discontinued by Jul 2018 2 Butler et al, Marked Expansion of Exocrine and Endocrine Pancreas With Incretin Therapy in Humans With Increased Exocrine Pancreas Dysplasia and the Potential for Glucagon-Producing Neuroendocrine Tumors, Diabetes, Vol. 62, Jul 2013 Egan et al, Pancreatic Safety of Incretin-Based Drugs - FDA and EMA Assessment, The New England Journal of Medicine 370;9, 27 Feb 2014 Source: IQVIA (formerly IMS) MIDAS, monthly data, Nov 2017 (Note: IQVIA data does not adequately capture rebates resulting in an overstatement of market value) FDA: US Food and Drug Administration; EMA: European Medicines Agency AAMEO: Africa, Asia, Middle-East and Oceania; J&K: Japan & Korea; LATAM: Latin America Source: Reported sales for FY 2017; IQVIA (formerly IMS) MIDAS, Nov 2017 novo nordisk
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