Investor Presentaiton

Neuroscience Anti-MTBR-Tau elF2B Activator Building an exciting portfolio in neurodegenerative and neuroinflammatory conditions Neurodegeneration/Neuroinflammation ☐ In Development ALS Alzheimer's Disease Huntington's Disease Anti-MTBR- elF2B Activator Tau mAb Multiple Sclerosis Parkinson's Disease TYK2i-CNS1 22 active programs in discovery Ill Bristol Myers Squibb™ 1. TYK2i-CNS to transition into clinic soon FAAH-MGLL Powered by internal & external innovation Not for Product Promotional Use 127

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