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Investor Presentaiton

Nurtec ODT - one of the strongest recent launches in biopharma March 2018 Positive pivotal Nurtec ODT efficacy studies(1) December 2018 February 2020 March 2020 Positive Nurtec ODT long- term safety study (2) FDA approval of Nurtec ODT for acute migraine (3) Positive Phase 3 Nurtec ODT migraine prevention study (4) May 2021 FDA approval of Nurtec ODT for migraine prevention (5) November 2021 May 2022 Biohaven Ex-U.S. collaboration with Pfizer (6) Pfizer to acquire Biohaven (7) Encouraging oral CGRP (8) volumes Total prescriptions (TRX)(9) Successful Nurtec ODT launch in US(10) Nurtec ODT global net revenue ($ in millions) Pfizer expects significant peak sales(7) 80,000 April 2020 64 463 1,668 1,302 912 2,177 Present 2020 2021 2022e 2023e 2024e 2025e CGRP: calcitonin gene-related peptide >$6bn 1. Biohaven press release, March 26, 2018. 2. Biohaven press release, December 10, 2018. 3. Biohaven press release, February 27, 2020. 4. Biohaven press release, March 30, 2020. 5. Biohaven press release, May 10. Visible Alpha consensus as of May 2022. ROYALTY PHARMA 27, 2021. 6. Biohaven press release, November 9, 2021. 7. Pfizer press release and presentation, May 10, 2022. 8. Oral CGRPs include Ubrelvy, Quilipta and Nurtec ODT. 9. IQVIA SMART: TRX volume to April 2022. 72
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