Investor Presentation Full Year 2021 slide image

Investor Presentation Full Year 2021

12 Investor presentation Full year 2021 Total RybelsusⓇ TRx volume is steadily growing in the US RybelsusⓇ and SGLT-21 uptake in the US² since respective launches NBRX count ...... (000s) RybelsusⓇ NBRX RybelsusⓇ TRX 10 8 6 4 2 2019 SGLT-2i NBRX SGLT-2i TRX TRx count (000s) 75 66 60 Time since launch (weeks) 2020 2021 91 97 103 109 45 46 30 115 2022 0 15 For the full year 2021, RybelsusⓇ sales approaches DKK 5 billion RybelsusⓇ has now been launched in 29 countries In the US: . • Successful RybelsusⓇ launch despite COVID-19 impacting the first year of launch RybelsusⓇ TRX steadily increasing, reaching +45,000 Rx per week Outside of the US: • In Japan, RybelsusⓇ has reached a 2.6% MOAD value market share following lift of the 14-day prescription limitation in December 2021 1SGLT-2i is an average of empagliflozin and canagliflozin script count. 2Rybelsus® is based on Oct 2019 focus launch. Each data points represents a rolling four-week average. Note: NBRx: New-to-brand prescriptions; RHS: Right hand side axis; HCP: Healthcare Professional; TRX: Total prescription data; MOAD: Modern oral anti-diabetics and includes SGLT-2is, DPP-IVis and Oral GLP-1. Source: IQVIA Xponent, Weekly (ending 7 January 2022) Novo NordiskⓇ
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