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Reimagining Medicine

Company overview Financial review Conclusions Appendix References Q2 growth driven by strong performance from EntrestoⓇ, KesimptaⓇ, PluvictoⓇ and KisqaliⓇ Q2 sales Entresto Sales USD million Growth vs. PY USD million 1,516 sacubitri/valsartan Kesimpta 489 (ofatumumab) 240 PLUVICTO™ KISQALI 493 185 ribociclib Ⓒ SCEMBLIX® 106 75 (asciminib) LEQVIO® 78 56 150 64 A LUTATHERA PROMACTA 583 49 (eltrombopag) X PIQRAY 130 45 (alpelisib) tablets Tafinlar. + Mekinist. 496 44 ILARIS (canakinumab) 316 41 230 391 250 Growth vs. PY CC 37% GROWTH 105% nm Strong growth (+71% cc); 66% expected to continue 248% 249% 75% 11% 54% 13% 17% Constant currencies (cc) is a non-IFRS measure; explanation of non-IFRS measures can be found on page 48 of Condensed Interim Financial Report. Unless otherwise noted, all growth rates refer to same period in PY. nm not meaningful. 5 Investor Relations | Q2 2023 Results ✓ NOVARTIS | Reimagining Medicine
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