Reimagining Medicine slide image

Reimagining Medicine

Existing brands Company overview Innovation: Pipeline overview Financial review Financial performance Novartis submission schedule Supplementary indications for existing brands Conclusions Appendix Innovation: Clinical trials References Abbreviations INNOVATION Cardiovascular Immunology Neuroscience Solid tumors Hematology Non-core TA project KisqaliⓇ 2023 ribociclib, LEE011 HR+/HER2- BC (adj) XolairⓇ omalizumab, IGE025 Food allergy Piqray® alpelisib, BYL719 Ovarian cancer 2024 JakaviⓇ ruxolitinib, INC424 Pediatrics Acute GVHD JakaviⓇ ruxolitinib, INC424 Pediatrics Chronic GVHD LutatheraⓇ 177Lu-oxodotreotide1 GEP-NET 1L G3 ScemblixⓇ ABL001 CML 1L 2025 CosentyxⓇ secukinumab, AIN457 GCA Leqvio® KJX839 Ped Hyperlipidemia ZolgensmaⓇ AVXS-101 OAV101 SMA IT denosumab GP2411 anti RANKL mAb BioS Adakveo SEG101 Sickle cell disease, pediatrics aflibercept SOK583 BioS Neovascular age-related macular degeneration Coartem® artemether + lumefantrine, COA566 Malaria uncompl., formula for <5kg ty AimovigⓇ erenumab, AMG334 Pediatric Migraine Cosentyx® secukinumab, AIN457 Tendinopathy CosentyxⓇ secukinumab, AIN457 Polymyalgia rheumatica Y KesimptaⓇ2 ofatumumab Multiple sclerosis, pediatrics. LeqvioⓇ KJX839 CVRR-LDLC BeovuⓇ brolucizumab, RTH258. Diabetic retinopathy PromactaⓇ eltrombopag, ETB115 Radiation sickness syndrome AtecturaⓇ indacaterol + mometasone, QMF149 Asthma, pediatrics 1. 177 Lu-dotatate in US. 2. Kesimpta and Mayzent: Pediatric study in multiple sclerosis run in conjunction (NEOS). 37 Investor Relations | Q2 2023 Results ≥2026 ty Leqvio® KJX839 Primary prevention MayzentⓇ2 siponimod, BAF312 Multiple sclerosis, pediatrics ty RydaptⓇ midostaurin, PKC412 Acute myeloid leukemia, pediatrics ScemblixⓇ ABL001 CML, 2L, pediatrics O NOVARTIS | Reimagining Medicine
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