Investor Presentation First Nine Months of 2022

123 Investor presentation First nine months of 2022 Insulin market size and volume share of growth and market share in Region China Region China Insulin market share and market size (DKK billion) Total 27% Long- acting Fast- acting 80% 2 51% Premix 82% 4 36% Human 3 6 Novo Nordisk Competitors Market growth A Market share 80% 14 3.9% +2.2% Insulin volume: market share 50% 60% 1.3% +4.4% 40% 49% 30% 40% 20% 33% 7.0% -0.7% 20% 7.6% 10% 5% 7.4% +2.6% 0% 0% Aug Aug 2019 2022 -NN market share 2.6% -4.2% Source: IQVIA, Aug 2022, LHS graph - Value, RHS Graph - Volume, MAT; NN: Novo Nordisk; Region China covers Mainland China, Taiwan, and Hong Kong NN share of growth Market growth (right axis) NN growth (right axis)

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