Investor Presentation

115 Investor presentation First six months of 2022 Insulin market size and volume market share in EMEA Insulin market share and market size (DKK billion) Total 49% Long- acting 40% Fast- 56% 12 acting 74% Premix 3 44% Human 3 19 Novo Nordisk Competitors Market growth A Market share 60% 37 2.9% +0.8% 4.4% +1.6% 40% 4.7% -0.4% 20% Insulin volume: market share -0.9% +1.9% 0% May -NN market share 2019 -7.5% 0.0% Source: IQVIA, May 2022, LHS graph - Value, RHS Graph - Volume, MAT, Europe, Middle East & Africa, Share of growth not depicted due to too high numbers; NN: Novo Nordisk EMEA 10% 48% 7% 3% 4% 2% 1% -2% May 2022 Market growth (right axis) NN growth (right axis)

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