Lundbeck Q3 2019 Financial Results
Lu AG06466: First-In-Class drug with broad potential in CNS
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*
Lu AG06466 modulates the
endocannabinoid system
preferentially in areas where
neuronal circuits are excessively
activated
Initial trials ongoing in
Tourette's and neuropathic pain
Phase lb trial in adult TS patients
demonstrated significant effects
across multiple endpoints of tic
reduction
200,000 patients in U.S. with
severe disease¹)
大
Exploratory phase Ila trial ongoing
(NCT03625453)
Initiated in October 2018
48 adult patients with Tourette's
Part 1: 8 weeks with daily
administration; Patients who
choose to enter Part 2: additional
4 weeks with daily administration
Change from baseline in Total Tic
Score of the Yale Global Tic
Severity Scale (YGTSS-TTS)
Headline results due in 2020
I
Lu AG06466: First-in-Class drug
with broad potential in CNS
Neuropsychiatric
disorders
Movement
disorders
Initial
indication
•
•
•
OCD
Agitation
ADHD
Parkinson's
Tardive
dyskinesia
Huntington's
Tourette's
31
1) NIH - National Institute of Neurological Disorders and Stroke
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