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Investor Presentaiton

Full year 2022 Delivered a landmark year Achieved double-digit turnover +10%, adj. operating profit growth +17%, excluding COVID-19 solutions Step change in commercial execution with growth across the portfolio: Specialty Medicines +29% (+15% excl. Xevudy) Vaccines +11% (+17% excl. pandemic adjuvant) General Medicines +1% COVID-19 solutions sales of £2.4bn R&D investment and strategic business development support future growth Absolute values at actual exchange rates (AER); changes at CER and full year 2022, unless stated otherwise. 1. Continuing results represents performance excluding discontinued operations 2. Excluding COVID-19 solutions GSK Turnover¹ +13% (+10%²) Adj. operating profit¹ +14% (+17%²) £29.3bn £8.2bn Adj. EPS¹ +15% 139.7p Full year 2023 guidance² Sales growth: 6-8% Free cash flow¹ £3.3bn Adj. operating profit growth: 10-12% Adj. EPS growth: 12-15% 6
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