Full Year 2023 Investor Presentation

116 Investor presentation Full year 2023 Insulin market size and volume share of growth and market share in International Operations Insulin market share and market size (DKK billion) Total 51% Long- Acting 40% Fast- acting 57% 15 Premix 78% 7 49% Human 6 Novo Nordisk 1Market growth is YTD current vs YTD previous year NN: Novo Nordisk 26 Competitors Note: Share of growth not depicted due to too high numbers; Market values are based on the list prices Source: IQVIA, Nov 2023, LHS graph - Value, RHS Graph - Volume, MAT, all countries Market growth1 A Market share 55 80% 55 -9.0% +0.1% Insulin volume: Market share Novo NordiskⓇ 10% 7% 60% -6.6% +1.4% 48% 4% 40% 1% -4.5% -1.3% -1% -2% 20% -4% -5% -15.7% -1.0% 0% -8% Nov Nov -19.0% +1.5% 2020 2023 NN market share -Market growth (Right Axis) NN growth (Right Axis)

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