Investor Presentaiton

Action after the Isolation Period is Over (1) Vector Gene Targeted Medical Action after the Isolation Period disease Institution/ Sponsor ADA ADA- Hokkaido deficiency Univ. RCV ( - ) in blood Hospital →Discharge HSV-TK recurrent Tsukuba and leukemia Univ. Retro ALNGFR (acute GVHD) Hospital /TAKARA RCV ( + ) in blood >>Continued isolation BIO Inc. MDR1 Breast Cancer cancer Institute Hospital of JFCR RCV ( Discharge - ) →RCV ( + ) after Re-isolation ( until patient tested negative for RCV)

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